Mammalian artificial chromosome pilot production facility: Large‐scale isolation of functional satellite DNA‐based artificial chromosomes
نویسندگان
چکیده
منابع مشابه
Bacterial artificial chromosomes improve recombinant protein production in mammalian cells
BACKGROUND The development of appropriate expression vectors for large scale protein production constitutes a critical step in recombinant protein production. The use of conventional expression vectors to obtain cell lines is a cumbersome procedure. Often, stable cell lines produce low protein yields and production is not stable over the time. These problems are due to silencing of randomly int...
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ژورنال
عنوان ژورنال: Cytometry
سال: 1999
ISSN: 0196-4763,1097-0320
DOI: 10.1002/(sici)1097-0320(19990201)35:2<129::aid-cyto4>3.3.co;2-1